ArticleRe-dilation of Coronary Arteries of a Child with H/O Atypical Kawasaki Disease, following Chickenpox: A Case Study
Tahera , M. Quamrul , Azmeri , Fahmida ,
Kawasaki disease (KD) is an acute vasculitis of medium sized arteries in childhood with unclear etiology that leads to coronary artery aneurysm (CAA) and ectasia in up to 25 % of untreated children. Typically, Kawasaki disease has a few traditional diagnostic criteria. Incomplete or atypical Kawasaki disease presents with a complex and variable dimension of clinical features. Though it etiology is unknown, there is evidence for some genetic susceptibility to Kawasaki disease as well as some link to infectious agents like varicella zoster. We are reporting one such child of atypical Kawasaki disease on follow up, who was on low dose aspirin and developed re-dilation of coronary arteries after exposure to varicella virus infection. Initially he was treated with intravenous immunoglobulin (IVIG) and appropriate dose of aspirin during acute stage of Kawasaki disease, six months before the infection of varicella zoster virus. Although the illness happened during COVID-19 pandemic situation, the baby did not have any symptoms of COVID-19 virus and could not do any laboratory test. We suspect the episode of chicken pox to be the probable cause of re-dilatation or coronary arteries in this child.
Atypical Kawasaki disease, coronary artery re-dilation, varicella zoster virus, COVID-19 pandemic, intravenous immunoglobulin (IVIg).